NCI Benchmarks |  |
Staudt elected to National Academy of Sciences
Louis Staudt, M.D., Ph.D., is the deputy chief of the Metabolism Branch in NCI’s Center for Cancer Research. In this video from March 2012, Staudt discusses the basic biology of targeted therapy for Diffuse B-cell Lymphoma and about ibrutinib, a drug with a high degree of efficacy—and only modest side effects—in the treatment of the ABC form of Diffuse B-cell Lymphoma.
A New Delivery for Cancer Drugs
The protein tumor necrosis factor-alpha (TNF-alpha) is a powerful weapon in the arsenal to control cancer. Unfortunately, as is the case with many potent cancer therapies, the use of TNF-alpha as an anti-cancer therapy has been severely limited. “It was so toxic that it caused death,” and researchers gave up on it, explains Scott [...]
Anuradha Budhu
Anuradha Budhu, Ph.D., heads a research team at the National Cancer Institute that recently uncovered an imbalance between saturated and unsaturated fats (such as palmitic or fatty acids) that occur in patients with a common liver cancer called hepatocellular carcinoma, or HCC. Budhu’s team also determined that HCC patients with high unsaturated fat levels had [...]
 EurekAlert! - Cancer |  |
UT Dallas study suggests new approach to fight lung cancer
(University of Texas at Dallas) Recent research has shown that cancer cells have a much different -- and more complex -- metabolism than normal cells. Now, scientists at the University of Texas at Dallas have found that exploiting these differences might provide a new strategy to combat lung cancer.
Scientists catch EGFR passing a crucial message to cancer-promoting protein
(University of Texas M. D. Anderson Cancer Center) Researchers have discovered and mapped the signaling network between two previously unconnected proteins, exposing a link that, if broken, could cut off cancer cell growth at its starting point.
Chemical probe confirms that body makes its own rotten egg gas, H2S, to benefit health
(Southern Methodist University) A new study confirms directly what scientists previously knew only indirectly -- that poisonous "rotten egg" gas hydrogen sulfide is generated by the body's blood vessel cells. Researchers made the confirmation by developing a chemical probe that lights up in reaction to rotten egg gas. The scientists observed the process in real-time through a microscope, said chemist Alexander Lippert, Southern Methodist University, Dallas. "This is going to open up many experiments for scientists," Lippert said.
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